ChIP is an enrichment of DNA bound by a particular protein, not a complete purification of the protein-bound DNA. As a result, ChIPs are unavoidably contaminated with chromatin bound non-specifically which can make data interpretation difficult. To solve these problems, Active Motif offers species-specific ChIP-IT^® Control Kits for real time or endpoint PCR. Control kits are ideal for ChIP antibody and primer set validation when run in parallel with your test samples. The control kit will help to confirm the chromatin preparation and immunoprecipitation procedures worked properly and allow you to assess the quality of your test antibody and primer sets.

The ChIP-IT^® Control qPCR Kits include a positive control antibody, a bridging antibody to enhance binding affinity of mouse monoclonal antibodies, a negative control antibody to evaluate non-specific binding and species-specific positive and negative control qPCR primers. The positive and negative control primer sets enable direct comparison of gene targets for the same antibody immunoprecipitation. This eliminates the variation that is seen when comparing a ChIP antibody result to that of a negative control IgG antibody, as each have different binding affinities.

Our original ChIP-IT^® Control Kits are designed for use in endpoint PCR. Each kit provides positive and negative control antibodies, bridging antibody to enhance the binding affinity of mouse monoclonal antibodies, a positive control PCR primer set as well as a PCR buffer/DNA loading dye that makes your PCR reactions ready to run on the gel straight out of the thermocycler.

美国Active Motif公司致力于细胞生物学和分子生物学研究试剂的开发与生产，是世界上最大的转录因子研究试剂生产商。为全球从事基因功能研究、基因表达调控及其编码蛋白研究的科研人员，提供高质量的产品和优质的服务。

Active Motif 公司是一家致力于细胞生物学和分子生物学研究用试剂的开发和生产的专业公司，是世界上最大的转录因子试剂生产商。为全球从事表观遗传学、核功能研究、基因表达调控及其编码蛋白研究的科学家，提供高品质的试剂和优质的服务。

其产品涉及ChIP-IT®染色质免疫共沉淀试剂盒，TransAM® 转录因子ELISA试剂盒，LightSwitch™萤光素酶报告系统，组蛋白纯化试剂，组蛋白乙酰转移酶活性检测试剂盒，组蛋白修饰ELISA试剂盒，Luminex®组蛋白H3多重分析试剂盒，甲基化DNA检测及富集试剂盒，FACE™磷酸化蛋白ELISA试剂盒，Ras GTPase活性检测试剂盒，核蛋白提取试剂盒，重组组蛋白，组蛋白及组蛋白修饰抗体，DNA甲基化相关抗体等。

Active Motif公司提供创新性的生物技术应用于多个研究领域，其产品对发现、破译和了解复杂的细胞功能提供了有力的帮助，同时Active motif公司不断的开发新产品，为生物工程领域的研究提供了可靠保证。 如其开发的NOMe-Seq试剂盒，是世界上首个可以分析同一DNA分子上多种表观修饰关系的试剂盒，通过高分辨率的核小体定位和甲基化谱测序，可对同一条DNA链进行核小体足迹和DNA甲基化谱分析，该产品也因此荣获《The Scientist》2013生命科学10大创新产品的称号。