Active Motif offers a large collection of full-length, high-quality recombinant proteins for many relevant drug targets for use in biochemical assays and high-throughput epigenetic drug discovery. Our proteins are manufactured to meet the highest standards of purity and activity required for conventional drug discovery assays, such as HTRF, mass spectrometry, AlphaLISA and AlphaScreen, and these assays are routinely incorporated into our quality control processes. We also provide a wide selection of histone substrates and small molecules for your epigenetic drug discovery assays.
Our recombinant proteins are available in small scale and bulk quantities. Inquire about placing a bulk order.
Recombinant nucleosomes are the most relevant substrate for many epigenetic assays.
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Browse our large collection of recombinant histones and modified histones.
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Our histone peptides are a simple and affordable option for use in a variety of biochemical and enzymatic assays.
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Comprehensive collection of recombinant bromodomain-containing proteins.
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Enzymes to study RNA modifications, such as m6A methylation.
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Highly active recombinant HAT and HDAC enzymes.
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Highly active recombinant HMT and HDM enzymes.
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Purified recombinant transcription factors, kinases, and other proteins for biochemical assays and high-throughput screening.
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美国Active Motif公司致力于细胞生物学和分子生物学研究试剂的开发与生产,是世界上最大的转录因子研究试剂生产商。为全球从事基因功能研究、基因表达调控及其编码蛋白研究的科研人员,提供高质量的产品和优质的服务。
Active Motif 公司是一家致力于细胞生物学和分子生物学研究用试剂的开发和生产的专业公司,是世界上最大的转录因子试剂生产商。为全球从事表观遗传学、核功能研究、基因表达调控及其编码蛋白研究的科学家,提供高品质的试剂和优质的服务。
其产品涉及ChIP-IT®染色质免疫共沉淀试剂盒,TransAM® 转录因子ELISA试剂盒,LightSwitch™萤光素酶报告系统,组蛋白纯化试剂,组蛋白乙酰转移酶活性检测试剂盒,组蛋白修饰ELISA试剂盒,Luminex®组蛋白H3多重分析试剂盒,甲基化DNA检测及富集试剂盒,FACE™磷酸化蛋白ELISA试剂盒,Ras GTPase活性检测试剂盒,核蛋白提取试剂盒,重组组蛋白,组蛋白及组蛋白修饰抗体,DNA甲基化相关抗体等。
Active Motif公司提供创新性的生物技术应用于多个研究领域,其产品对发现、破译和了解复杂的细胞功能提供了有力的帮助,同时Active motif公司不断的开发新产品,为生物工程领域的研究提供了可靠保证。 如其开发的NOMe-Seq试剂盒,是世界上首个可以分析同一DNA分子上多种表观修饰关系的试剂盒,通过高分辨率的核小体定位和甲基化谱测序,可对同一条DNA链进行核小体足迹和DNA甲基化谱分析,该产品也因此荣获《The Scientist》2013生命科学10大创新产品的称号。